December 23, 2017

Biophysics of Computation: Information Processing in Single by Christof Koch PDF

By Christof Koch

Neural community examine usually builds at the fiction that neurons are uncomplicated linear threshold devices, thoroughly neglecting the hugely dynamic and complicated nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: info Processing in unmarried Neurons demanding situations this suggestion, utilizing richly distinctive experimental and theoretical findings from mobile biophysics to provide an explanation for the repertoire of computational services on hand to unmarried neurons. the writer indicates how person nerve cells can multiply, combine, or hold up synaptic inputs and the way details should be encoded within the voltage around the membrane, within the intracellular calcium focus, or within the timing of person spikes.
Key themes lined contain the linear cable equation; cable thought as utilized to passive dendritic bushes and dendritic spines; chemical and electric synapses and the way to regard them from a computational viewpoint; nonlinear interactions of synaptic enter in passive and lively dendritic bushes; the Hodgkin-Huxley version of motion power new release and propagation; section house research; linking stochastic ionic channels to membrane-dependent currents; calcium- and potassium-currents and their function in details processing; the position of diffusion, buffering and binding of calcium, and different messenger structures in info processing and garage; brief- and long term types of synaptic plasticity; simplified types of unmarried cells; stochastic features of neuronal firing; the character of the neuronal code; and unconventional versions of sub-cellular computation.
Biophysics of Computation: details Processing in unmarried Neurons serves as an amazing textual content for complicated undergraduate and graduate classes in mobile biophysics, computational neuroscience, and neural networks, and should attract scholars and execs in neuroscience, electric and laptop engineering, and physics.

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Biophysics of Computation: Information Processing in Single Neurons (Computational Neuroscience Series) by Christof Koch

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